Is there an Iron Supplement Which Does not Cause Diarrhea?

Oral iron therapy is associated with gastrointestinal side effects, including nausea, constipation, and diarrhea, that can compromise compliance and are the main reason for discontinuation(Dr. Ralph Green, hematologist)

Iron supplements are a popular treatment for iron deficiency anemia, but they can cause tummy troubles like diarrhea, which nobody wants. Luckily, there's a new type of iron supplement that's effective and doesn't cause those pesky side effects. It's called nano iron, and it's made up of tiny nanoparticles that are absorbed by your body quickly, which solves the issue completely.

Nano iron is more effective than traditional supplements at increasing hemoglobin levels and has fewer side effects. (1)  Plus, it's easy for your body to use, so you'll get the benefits you need without any nasty surprises. So if you're looking for an iron supplement that won't cause diarrhea, nano iron is definitely worth checking out.

Is there an Iron Supplement Which Does not Cause Diarrhea?

Why Does Iron Supplementation Cause Diarrhea?


Diarrhea is a common and unpleasant side effect of traditional iron supplements. To understand why this happens, let's take a closer look at the science of iron absorption and how it can lead to this gastrointestinal issue.

When you take an iron supplement, the iron enters your digestive system and is absorbed primarily primarily in the duodenum and upper jejunum of the small intestine. This absorption process is regulated by a protein called hepcidin. However, traditional iron supplements tend to release a large amount of iron at once, overwhelming the body's natural regulatory mechanisms. As a result, not all of the iron is absorbed, and the unabsorbed iron continues to travel through the digestive tract.

This surplus iron can disrupt the balance of the gut microbiome, which is the community of microorganisms that live in your digestive system. When the gut microbiome is disrupted, it can lead to diarrhea. Additionally, the unabsorbed iron can draw water into the gut, causing loose stools and cramping. In some cases, the free iron can even damage the intestinal lining, further contributing to diarrhea.

How Iron Upsets Your Stomach

Iron can upset your stomach when the amount ingested surpasses what your body can absorb. When the capacity to absorb iron is exceeded, the excess remains in the gastrointestinal tract.

This unabsorbed iron can lead to several issues:

  1. Microbiome Disruption: Excess iron alters the growth patterns of gut bacteria, leading to an imbalance. Some bacteria that thrive on iron can outcompete others, potentially leading to gas, bloating, and altered stool consistency.

  2. Osmotic Effect: Iron that remains in the colon can attract water into the bowel. This osmotic effect results in watery stools, or diarrhea, as the body attempts to flush out the unabsorbed iron.

  3. Mucosal Irritation: The excess iron can also irritate the lining of the gastrointestinal tract, causing inflammation or gastritis, which may contribute to stomach discomfort and exacerbate diarrhea.


All of these persistent gastrointestinal side effects can discourage people from adhering to their iron supplement regimen.

What Iron Supplements Don't Upset Your Stomach?

Nano Iron is undoubtedly the easiest iron supplement on the stomach, based on our research.100% gentle on the stomach, Nano Iron specifically engineered to minimize gastrointestinal side effects that are commonly associated with other forms of iron supplements.

In the broader market, iron bisglycinate, also known as gentle iron, is another option that is reputed to be easier on the digestive system. This form is chelated, meaning the iron is bound to amino acids, making it more absorbable and less likely to cause constipation and stomach pain.However, while it is gentler, it is not entirely free from causing side effects. Some individuals may still experience digestive issues, although these tend to be less severe

Liquid iron supplements are also considered to be gentler on the stomach, as they can be more readily absorbed.

Time-release iron supplements release iron slowly, which can lessen gastrointestinal distress compared to those that release iron immediately upon ingestion.

Nano Iron: an Easily Tolerated Iron Supplement that Doesn't Cause Diarrhea or an Upset Stomach

Nano Iron is a cutting-edge iron supplement has been specifically designed to mitigate the gastrointestinal issues often experienced with conventional iron supplements, providing a more comfortable and effective way to boost your iron levels.

Nano Iron, also known as nanoparticulate iron or iron nanoparticles, is a form of iron that has been reduced to microscopic particles, typically in the range of 1 to 100 nanometers in size. These tiny particles offer several advantages over traditional iron supplements, particularly in terms of bioavailability and reduced side effects like diarrhea.

The key to Nano Iron's effectiveness in preventing diarrhea lies in its enhanced absorption. The minuscule size of the iron nanoparticles allows for a greater surface area, leading to improved absorption in the small intestine. This increased absorption means that less unabsorbed iron reaches the colon, reducing the likelihood of disrupting the gut microbiome and irritating the gastrointestinal lining. As a result, the risk of developing diarrhea is significantly diminished, or even eliminated.

Conclusion: The Best Iron Supplement for a Sensitive Stomach

Try Nano Iron today, a revolutionary form of iron which is eradicating digestive distress for thousands of people around the world.

Gentle on the stomach, this tasteless, odourless iron liquid is ideal for the whole family, and even your pets.


What is the most easily tolerated iron supplement? Nano Iron is widely regarded as the most easily tolerated iron supplement, as it is specifically designed to minimize side effects like diarrhea and upset stomach, which are common with other iron supplements. Its nanoparticle technology enables direct absorption into the bloodstream, reducing the impact on the stomach and gastrointestinal tract.

Why do iron tablets upset my stomach? Iron tablets commonly upset the stomach due to the irritation they can cause to the stomach lining and their potential to disrupt the gut microbiome. This can result in side effects like nausea, cramps, and diarrhea. Nano Iron's smaller particle size and higher absorption rate can significantly reduce these adverse effects.

Which iron is gentlest on the stomach? While iron bisglycinate is considered gentle, Nano Iron is often preferred for its gentle nature and minimal side effects. Its innovative formulation reduces the likelihood of stomach upset, making it a superior choice for individuals with sensitive digestive systems or who have experienced side effects from other iron supplements.

How should you take iron supplements to avoid gastric upset? Taking iron supplements with food can mitigate gastric upset. Nano Iron, due to its high absorbency and lower impact on the gastrointestinal tract, can be taken with or without food, making it a convenient option. Regardless of the supplement type, it is always advisable to follow the dosing recommendations of a healthcare provider.

What happens if you can't tolerate iron supplements? If traditional iron supplements cause intolerable side effects, Nano Iron is an alternative that tends to be better tolerated due to its innovative form, which typically causes zero side effects for most people. If oral supplements still aren't suitable, a healthcare provider may recommend intravenous iron therapies.



(1) Darwish AMG, Soliman TN, Elhendy HA, El-Kholy WM. Nano-encapsulated Iron and Folic Acid-Fortified Functional Yogurt Enhance Anemia in Albino Rats. Front Nutr. 2021 Apr 7;8:654624. doi: 10.3389/fnut.2021.654624. PMID: 33898503; PMCID: PMC8058429.

(2) Green, R. (2011). Anemias beyond B12 and iron deficiency: the buzz about other B’s, elementary, and nonelementary problems. Hematology Am Soc Hematol Educ Program, 2011(1), 527-537.

(3) Singh K, Sethi Chopra D, Singh D, Singh N. Nano-formulations in treatment of iron deficiency anaemia: An overview. Clin Nutr ESPEN. 2022 Dec;52:12-19. doi: 10.1016/j.clnesp.2022.08.032. Epub 2022 Sep 6. PMID: 36513444.